Malignant Brenner tumor associated with a germline BRCA2 mutation
نویسندگان
چکیده
منابع مشابه
Malignant Brenner tumor associated with a germline BRCA2 mutation
•The first woman with a Malignant Brenner tumor and a BRCA2 mutation is described.•Not all women with epithelial ovarian cancers are referred for genetic counseling.•Women should be referred for genetics regardless of how rare the histology.
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Brenner tumor is a relatively uncommon neoplasm. It constitutes 1.4–2.5 % of all ovarian tumors and has a predilection for the postmenopausal women. Most Brenner tumors are benign, with only 2–5 % being malignant. The malignant components of the tumor, which show heterogeneous epithelial growth and atypia with intervening stroma, consist of transitional cells, squamous or undifferentiated carci...
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ژورنال
عنوان ژورنال: Gynecologic Oncology Reports
سال: 2017
ISSN: 2352-5789
DOI: 10.1016/j.gore.2017.05.006